HIVH合并肝炎.ppt

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1、治疗的时机？治疗影响的变量IFNIFNLAMLAMETVETVFTCFTCTDFTDFADVaADVaNo.of No.of patientspatients8787b b230230b b51513333200200b b3535Duration Duration(weeks)(weeks)12122424484824244848242448484848192192Anti-HBV Anti-HBV activity activity tested in tested in HIV HIV patientspatientswtwtwtwtLMV-RLMV-Rwtwtwt,LAM-Rwt,LA

2、M-RLAM-RLAM-RHBV DNA HBV DNA decline decline(log(log1010 cp/mcp/mL)L)26%26%c c2.72.73.63.64.44.44.74.76 6a aHBeagHBeagseroconversion seroconversion(%)(%)9 911114 47 7ALT ALT normalizatnormalization(%)ion(%)1212202030305050494935356666a aHistological Histological improvemenimprovement t33-5033-50a a