世卫组织-人工智能健康伦理与治理：大型多模式模型指南（英）-2024.docx

IanizationEthicsandgovernanceofartificialintelligenceforhealthGuidanceonlargemulti-modalmodelsWorldHealthOiganizationEthicsandgovernanceofartificialintelligenceforhealthGuidanceonlargemulti-modalmodelsISBN978-92-4-008475-9(electronicversion)ISBN978-92-4-008476-6(printversion)©WorldHealthOrganization2024Somerightsreserved.ThisworkisavailableundertheCreativeCommonsAttribution-NonCommerciaI-ShareAIike3.0IGOlicence(CCBY-NC-SA3.0IGO;https:/creativecommons.Org/licenses/by-nc-sa/3.0/igo).Underthetermsofthislicence,youmaycopy,redistributeandadapttheworkfornon-commercialpurposes,providedtheworkisappropriatelycited,asindicatedbelow.Inanyuseofthiswork,thereshouldbenosuggestionthatWHOendorsesanyspecificorganization,productsorservices.TheuseoftheWHOlogoisnotpermitted.Ifyouadaptthework,thenyoumustlicenseyourworkunderthesameorequivalentCreativeCommonslicence.Ifyoucreateatranslationofthiswork,youshouldaddthefollowingdisclaimeralongwiththesuggestedcitation:"ThistranslationwasnotcreatedbytheWorldHealthOrganization(WHO).WHOisnotresponsibleforthecontentoraccuracyofthistranslation.TheoriginalEnglisheditionshallbethebindingandauthenticedition,AnymediationrelatingtodisputesarisingunderthelicenceshallbeconductedinaccordancewiththemediationrulesoftheWorldIntellectualPropertyOrganization,(http:/www.wipo.int/amc/en/mediation/rules/).Suggestedcitation.Ethicsandgovernanceofartificialintelligenceforhealth.Guidanceonlargemulti-modalmodels.Geneva:WorldHealthOrganization;2024.1.icence:CCBY-NC-SA3.0IGO.Cataloguing-In-Publication(CIP)data.CIPdataareavailableathttp:/apps.who.int/iris.Sales,rightsandlicensing.TopurchaseWHOpublications,seehttp:/apps.who.int/bookorders.TosubmitrequestsforCommercicensing,seehttp:/www.who.int/about/licensing.Third-partymaterials.Ifyouwishtoreusematerialfromthisworkthatisattributedtoathirdparty,suchastables,figuresorimages,itisyourresponsibilitytodeterminewhetherpermissionisneededforthatreuseandtoobtainpermissionfromthecopyrightholder.Theriskofclaimsresultingfrominfringementofanythird-partyownedcomponentintheworkrestssolelywiththeuser.Generaldisclaimers.ThedesignationsemployedandthepresentationofthematerialinthispublicationdonotimplytheexpressionofanyopinionwhatsoeveronthepartofWHOconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries.Dottedanddashedlinesonmapsrepresentapproximateborderlinesforwhichtheremaynotyetbefullagreement.Thementionofspecificcompaniesorofcertainmanufacturers*productsdoesnotimplythattheyareendorsedorrecommendedbyWHOinpreferencetoothersofasimilarnaturethatarenotmentioned.Errorsandomissionsexcepted,thenamesofproprietaryproductsaredistinguishedbyinitialcapitalletters.AllreasonableprecautionshavebeentakenbyWHOtoverifytheinformationcontainedinthispublication.However,thepublishedmaterialisbeingdistributedwithoutwarrantyofanykind,eitherexpressedorimplied.Theresponsibilityfortheinterpretationanduseofthemateriallieswiththereader.InnoeventshallWHObeliablefordamagesarisingfromitsuse.Graphicsdesign:JoannaSleigh(ETHZurich,Zurich,Switzerland)1.ayout:ImprimerieCentrale(1.uxembourg)ContentsAcknowledgementsvAbbreviationsviiExecutivesummaryviii1 Introduction11.1 Significanceof1.MMs31.2 WHOguidanceonethicsandgovernanceofAlforhealth4,Applications,challengesandrisksof1.MMs72 Applicationsandchallengesofuseof1.MMsinhealth82.1 Diagnosisandclinicalcare82.2 Patient-centredapplications122.3 Clericalfunctionsandadministrativetasks162.4 Medicalandnursingeducation172.5 Scientificandmedicalresearchanddrugdevelopment173 Riskstohealthsystemsandsocietyandethicalconcernsaboutuseof1.MMs203.1 Healthsystems203.2 Compliancewithregulatoryandlegalrequirements233.3 Societalconcernsandrisks24AEthicsandgovernanceof1.MMsinhealthcareandmedicine314 Designanddevelopmentofgeneral-purposefoundationmodels(1.MMs)344.1 Riskstobeaddressedduringthedevelopmentofgeneral-purposefoundationmodels(1.MMs)344.2 Measuresdeveloperscantaketoaddressriskswithgeneral-purposefoundationmodels(1.MMs)354.3 Governmentlaws,policiesandpublicsectorinvestments394.4 Open-source1.MMs415 Provisionwithgeneral-purposefoundationmodels(1.MMs)455.1 Riskstobeaddressedwhenprovidingahealth-careserviceorapplicationwithageneral-purposefoundationmodel(1.MM)455.2 Measuresthatgovernmentscanintroducetoaddresssuchrisksandethicalprinciplesthatshouldbeupheld466 Deploymentwithgeneral-purposefoundationmodels(1.MMs)536.1 Riskstobeaddressedwhendeployingahealth-careserviceorapplicationwithageneral-purposefoundationmodel(1.MM)536.2 On-goingresponsibilitiesofdevelopersandprovidersduringdeployment546.3 Responsibilitiesofdeployers546.4 Governmentprogrammesandpractices557 1.iabilityfor1.MMs588 Internationalgovernanceof1.MMs60References62Annex.Methods77AcknowledgementsDevelopmentofthisWorldHealthOrganization(WHO)guidancewasledbyAndreasReis(co-leadofthe